Biological Assay of Diabetic Children Snacks Prepared from Plant Sources

This work was aimed to prepare high nutririve value snacks for diabetic children and as ablood sugar lowering materials. Four snacks for diabetic children of high nutritive value were prepared using some plant seeds (black rice, lupine and germinated fenugreek seeds) and leaves (mulberry and olive leaves). The effect of sugar substitution on biological properties of prepared snacks using different levels of natural and artificial sweeteners {stevia, high fructose corn syrup (HFCS)} and olive oil were carried out.
Extending feeding albino rats for six weeks on any investigated snacks which contained plant sources such as seeds and leaves caused a continuous decrease in glucose level of rats. Snack 2 groups which were (120.25 mg/dl) showed lowest blood glucose level after nigative control (108.25 mg/dl). It was noticed that rats group fed on control (-) was the highest body weight gain (35.75) with being significantly different with other rats groups fed on snacks compared with control (+) showed the lowest BWG (-17.67). For food daily intake, it was clearly that it increased in all treated groups compared with control positive group (17.68) with being snack 2 had the highest food intake (17.97) comparing with control negative (17.75). FER ranged between 1.64 to 1.96 in snack rat groups comparing with control (-). Cotrol snack were the highest FER comparing with control negative which recorded (2.02).
Snack 1 had low content of cholesterol (97.05 mg/dl). The highest HDL-C was found to be in control snacks fellowed by snacks 2 as (55.36 mg/dl) and (54.32 mg/dl), respectively. All treatments decreased serum LDL levels at different degrees (22.18 to 95.48 mg/dl). Rats groups fed on snack 2 were the lowest LDL-C content (22.18 mg/dl). The highest GOT content was (76.62) found in rat groups fed on snack 3. All rat groups fed on snack 1 recorded value less than that of control positive (28.53) as (27.19), respectively. Feeding rat groups on diabetic children diets effected positively on high density lipoprotein cholesterol (HDL-C) and negatively on cholesterol, low density lipoprotein cholesterol (LDL-C) and triglyceride as well as reducing glutamic oxalacetic transaminase (GOT) and glutamic pyruvic transaminase (GPT).