Authors
1
Faculty of Specific Education
2
Department of Nutrition and Food Science - Faculty of Home Economics - Menoufia University - Shebein El-Kom - Egypt
3
Ashmoun Educational Administration - Elshaheed Elsaed preparatory school specializing in home economics
Abstract
This investgation aimed to evaluate the nutraceutical and therapeutic effects of delonix regia leaves and pods on kidneys vitality in rats inflicted with renal failure. 35 male albino rats weighing 150±10g were divided into five groups (n=7 rats); one group kept as control negative (C -ve), while the rest four groups injected gentamicin at a dose of 100 mg/kg b. wt., for 7 days to induce renal failure, one group left as control positive (C +ve), while the other three groups fed on 5% of the diet of delonix regia pods, leaves and mixture of them each, for 45 consecutive days. At the end of experiment, body weight gain, food intlke and feed efficiency ratio were calculated, Moreover, kidney functions (creatinine, urea and uric acid), triglycerides (T.G), total cholesterol (T.C), high density lipoprotein (HDL), low denisty lipoprotein (LDL), very low denisty lipoprotein (VLDL), total protein, and liver enzymes (AST and ALT) were determined, as soon as kidneys histopathological. All rats fed on 5% of the diet of delonix regia pods, leaves and mixture of them each showed significant decrease in body weight gain, feed efficiency ratio, kidney functions, triglycerides, total cholesterol, low denisty lipoprotein, very low denisty lipoprotein and liver enzymes but significant increase in total protein and high density lipoprotein, furthermore, an improvement in kidneys histopathological examinations were occured. This study revealed that delonix regia had positive nutraceutical and therapeutic effects on kidneys vitality in rats inflicted with renal failure without side effects related to other body functions.
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