Evaluating the Efficiency of Yohimbe, Horny goat weed and Maca Powder against Testicular Damage Induced by Cadmium Chloride in Male Rats

Authors

1 Department of Nutrition and Food Science, Faculty of Home Economics, Menoufia University, Shebin El-kom, Egypt.

2 Faculty of Home Economics Dept. of Nutrition and Food Science Menoufia university

Abstract

The purpose of this study is to determine the effectiveness of some plants against testicular damage caused by cadmium chloride in male rats. Thirty-six adult male albino rats weighing 150 ± 20 g were split into two major groups at random. The first main group consisted of six rats and was considered as negative control group, as they were fed on basal diet only. The second main group (30 rats) received an intra-peritoneal injection of two milligrams of cadmium chloride per kilogram of body weight to injure their testicles. Five groups were then created from this second main group, each containing six rats. One of the five groups was designated as a positive control group, while the other four groups were fed on yohimbe, horny goat weed, maca powder and their mixture at 5% of the diet for 28 days, respectively. The testes were extracted for histopathological examination and evaluation of antioxidant enzyme activity. The findings indicated that, when compared to the positive control group, consuming 5% of yohimbe, horny goat weed, maca powder and their mixture for 28 days led to significant increases in the levels of the serum sex hormones (luteinizing hormone (LH), testosterone (T) and follicle-stimulating hormone (FSH)), in addition to increasing the activity of antioxidant enzymes in testicular tissue. However, there were significant decreases in the indicators for kidney and liver function, lipid profiles and serum glucose level

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